In the comics, the Venom symbiote was initially worn by Peter Parker as a Spider-Man suit after he finds it on another planet before eventually separating and bonding with Eddie Brock. However, the movie makes the symbiotes independent discoveries of the Life Foundation, removing any connection to Spider-Man whatsoever. Indeed, the giant “white spider” insignia that typically appears on Venom’s chest is absent.

Every time the Venom Symbiote is referred as a “parasite” by other characters, it throws a hissy fit and makes threats that ultimately go nowhere. Likewise, Eddie is called out as a “loser” and often by the Symbiote itself.