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The name Engineer was given by Elizabeth Shaw and Charlie Holloway due to the lifeform being responsible for engineering the human race. Before the release of Prometheus, the Engineers were originally dubbed as the "Space Jockeys". The nickname was attached to it during production on Alien.
Scott has stated he has no idea who christened the creature. People needed something to call this creature, and somehow Space Jockey stuck. But the creature has also had a host of other names, including the Pilot (H. R. Giger's original nickname for it), Pilots, James Cameron called it the "Big Dental Patient", and later in the novel Aliens: Original Sin as Mala'kaks.
The central theme in Prometheus concerns the eponymous Titan of Greek mythology who defies the gods and gifts humanity with fire, for which he is subjected to eternal punishment. The gods want to limit their creations in case they attempt to usurp the gods.
The film deals with humanity's relationship with the gods - their creators - and the consequence of defying them. A human expedition intends to find God and receive knowledge about belief, immortality and death. They find superior beings who appear god-like in comparison to humanity, and the Prometheus crew suffer consequences for their pursuit.