Chelios visits Carlito at his penthouse and asks him to help find an antidote, as well as to find and kill Verona and his crew.
My name is Chev Chelios, and today is the day I die. Plot: A hit man (Jason Statham) learns that a poison injected into his body will kill him if his heart rate drops too much. Now he must exact his revenge on the people who injected him before he takes his last breath.
At the very end of the credits, we see Crank as if it was a retro video game. Chev shoots two henchmen, then he takes a needle containing drugs and goes into RAMPAGE mode and runs fast. He runs into another henchman who injects him with The Bejing Cocktail, the camera zooms in on Chev’s heart which explodes and blood splatters on the screen. And the words Game Over appears on the screen.
The word “cunt” was not originally going to be shown. The line was written in the script, but the word’s presence on Jason Statham’s forehead was a last minute inclusion by editor Brian Berdan granted by Mark Neveldine and Brian Taylor.
Chelios goes to the rooftop of the hotel and meets with Verona, Carlito, and his henchmen. Carlito takes out a syringe, filled with the same poison used by Verona. As he is about to kill Chelios by injecting the second dose into him, Don Kim, revealed to be alive as Chelios spared him, arrives with his Triads to assist Chelios and a shootout follows. During the battle, several of Don Kim’s and all of Carlito’s men are killed. Carlito tries to escape with his private helicopter, but Chelios manages to catch up to him and holds him at gunpoint. Before Chelios can kill Carlito, Verona sneaks behind and injects Chelios with the syringe, after which Chelios collapses. Carlito himself is betrayed by Verona, who shoots him to death and then tries to escape with his helicopter.
Chelios manages to stand up, boards the helicopter, and engages in a fight with Verona. After some struggle, Chelios manages to pull Verona out of the helicopter and while mid-air, Chelios proceeds to snap Verona’s neck, killing him. While falling, Chelios calls Eve on his cell phone to apologize for not coming back. Chelios hits a car, bounces off it and lands right in front of the camera. In the last shot, it is implied that his adrenaline is indeed still flowing fast; his nostrils flare, he blinks, and two heartbeats are heard.
Chelios visits Carlito at his penthouse and asks him to help find an antidote, as well as to find and kill Verona and his crew. Carlito says there is no antidote and only confirms that Carlito and Verona are working together. Carlito tells Chelios how he will use his death as a scapegoat against the Chinese. An angered Chelios leaves Carlito’s penthouse to find Verona. Through Chelios’ street contact, a transvestite named Kaylo (Efren Ramirez), he finds Alex at a restaurant and unsuccessfully interrogates him about his brother’s whereabouts before killing him. Chelios phones Verona through Alex’s phone and tells him of his brother’s death, prompting Verona to send thugs after Eve as a revenge. Chelios rushes to pick up Eve before Verona’s thugs get to her. Chelios reveals his true profession to her and that he was planning to retire to spend more time with her.