comprised of eight volumes published from 1985 to 2003:
- Morbus Gravis,
- Morbus Gravis 2: Druuna,
- The Forgotten Planet and Clone
The series is noteworthy for featuring perhaps the most realistic-looking and explicit content in terms of both graphic violence and sex in comics.
Serpieri has also published numerous sketchbooks, such as Obsession, Druuna X, Druuna X 2, Croquis, Serpieri Sketchbook, Serpieri Sketchbook 2 and The Sweet Smell of Woman.